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WHO warns about Covid-19 variant PJ.2.1

By , based on Algérie 360

WHO warns about Covid-19 variant PJ.2.1Illustrative image · Edward Jenner · Pexels · Licence Pexels

WHO warns about Covid-19 variant PJ.2.1, whose symptoms may resemble flu or a cold, and recalls that biological tests are needed to identify the infectious agent. Detected in Canada in May 2026, it is rapidly increasing in the United States, according to RIA Novosti citing WHO.

The World Health Organization (WHO) says that symptoms of Covid-19 variant PJ.2.1 can be confused with those of flu or a cold. A clinical examination is not sufficient to identify the agent responsible for a respiratory infection and biological tests remain necessary when the result is to guide treatment or public health decisions, according to a WHO statement reported by RIA Novosti on 8 November.

First detected in Canada in May 2026, PJ.2.1 descends from the JN.1 lineage, which originated from the Omicron family. In the United States, wastewater surveillance shows that its share is increasing rapidly. Initial laboratory data indicate that antibodies produced after a booster adapted to variant LP.8.1 continue to neutralise PJ.2.1, with effectiveness about 1.8 times lower, according to data cited by Algérie 360.

PJ.2.1 differs, however, in having a greater ability to bind to the ACE2 receptor present on the surface of human cells, which could favour its transmission. WHO has included it among the emerging lineages to be examined ahead of its next meeting on the composition of Covid-19 vaccines. Its Technical Advisory Group on Vaccine Composition (TAG-CO-VAC) had called on researchers and manufacturers to provide analyses in a statement published on 27 October 2026.

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